Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations

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Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations.

Clonal emergence of group A streptococci (GAS) with reduced susceptibility to fluoroquinolones (FQs) has been increasingly reported. Non-susceptibility is associated with various point mutations in the target-encoding genes and has only been described in a few emm types. We used a well-characterised GAS clinical paediatric collection from Brussels (Belgium) and Brasília (Brazil) to analyse the ...

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Two clinical isolates of viridans group streptococci (VS) with different degrees of susceptibility to optochin (OPT), i.e., fully OPT-susceptible (Opt(s)) VS strain 1162/99 (for which the MIC was equal to that for Streptococcus pneumoniae, 0.75 micro g/ml) and intermediate Opt(s) VS strain 1174/97 (MIC, 6 micro g/ml) were studied. Besides being OPT susceptible, they showed characteristics typic...

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Re: role of non-group a streptococci in acute pharyngitis.

BACKGROUND The role of non-group A streptococci (non-GAS) as pathogens of acute pharyngitis is controversial. Data are limited and conflicting on whether these bacteria are true pathogens of pharyngitis and whether treatment is indicated in all cases or just select cases. However, non-GAS are well-documented as being pathogens of other diseases, including neonatal sepsis, pneumonia, endocarditi...

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Fluoroquinolone-Resistant Group B Streptococci in Acute Exacerbation of Chronic Bronchitis

1. Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006;19:531–45. 2. Mizutani T, Endoh D, Okamoto M, Shirato K, Shimizu H, Arita M, et al. Rapid genome sequencing of RNA viruses. Emerg Infect Dis. 2007;13:322–4. 3. Sakai K, Mizutani T, Fukushi S, Saijo M, Endoh D, Kurane I, et al. An improved procedure for rapid ...

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Vaccination equally enables both genetically susceptible and resistant mice to control infection with group A streptococci.

There is substantial evidence that host genetic factors are important in determining susceptibility to infection with group A streptococci (GAS). Several studies have revealed that, similarly to humans, a genetic component may be important in determining susceptibility to GAS infection in mice. Thus, C3H/HeN mice are much more susceptible to streptococcal infection than BALB/c mice. We have det...

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ژورنال

عنوان ژورنال: International Journal of Antimicrobial Agents

سال: 2009

ISSN: 0924-8579

DOI: 10.1016/j.ijantimicag.2009.01.012